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Acute Disseminated Encephalomyelitis Neurol 56:1313-1318,1257, Schwarz,S.,et al, 2001 See this aricle in Pubmed Article Abstract Many patients initially diagnosed with ADEM develop clinically definite MS upon long-term follow-up. The authors found no useful diagnostic criteria for the differentiation of a first episode of MS from monophasic ADEM. The term ADEM may s till be employed as a description of a clinical syndrome, but should not be used as a distinct entity until reliable diagnostic criteria have been developed.

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